• Spada Ostia
• Spada Mac Os Update

Quick Facts

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Overview

The Spada 2000 is an all-weather, day and night, low-to-medium altitude air defense system (LOMADS), developed by European-Based MBDA Missile Systems. The Spada uses Aspide 2000 SAMs, which use a proximity fuse to detonate its fragmentation warhead.[i] Aspide 2000 missiles have a range of about 25 km and can intercept incoming projectiles like hostile aircraft before they release stand-off weapons.[ii] The system has a radar with a 60 km range and is able to track up to 100 targets at the same time.[iii] Additionally, the radar is electronic countermeasure (ECM) resistant. The Spada is also road-mobile and interoperable; it can coordinate with up to 10 VSHORADS within a 10 km radius.[iv] The Spada 2000 system consists of a detection center and either two or four firing sections. Each section is equipped with two missile launchers which have six ready-to-fire Aspide 2000 missiles.

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Strategic Implications

A critical military advantage afforded by the Spada 2000 lies in the fact that its long-range allows for targeting and destroying hostile aircraft before they can deploy standoff weapons.[v] This means that the Spada can be used in very effective and hard-to-breach air denial set-ups. The Spada is also very flexible, allowing it to take control of other anti-aircraft weapon systems such as medium-caliber guns, making it a versatile weapon for any situation.[vi]

Timeline

July 2010: Spada 2000 integrated into the Pakistani Air Force[vii]

September 2007: Pakistan Air Force to receive Spada 2000 System

March 2007: Kuwait orders the upgrade of its Aspide missile systems to the Aspide 2000/Spada 2000 configuration

Recent News

References

[vi] Ibid.

Released:

Find splicing-led, functional changes of the proteome.

Project description

spada

spada (Splicing-led Protein Alterations Discovered Agilely) is a tool to study the functional impact of alternative splicing changes in case-control studies. The alterations are represented as isoform switches i.e. the situation when cases are best represented by one isoform, while controls are best represented by a different one. Then, spada is able to predict which protein features are changing between both isoforms, and their impact on the protein-protein interaction network.

To start using spada, simply install it with

This package has two main functionalities:

• Calculating isoform switches from case-control transcript expression data:
• Predicting the effects of splicing on the protein structure and the interactome of a set of switches:

For detailed information on how to use spada, please visit the wiki.

Documentation

Citation

If you use spada in a scientific publication, we would appreciate citations:

Climente-González, H., Porta-Pardo, E., Godzik, A., and Eyras, E. (2017). The Functional Impact of Alternative Splicing in Cancer.Cell Reports 20, 2215–2226.

Related projects

• smartas: we applied spada to transcriptomics data from the TCGA. This repository contains the code for the analyses and the main conclusions.

Release historyRelease notifications RSS feed

1.26.5

1.26.4

1.26.3

1.26.2

1.26.1

1.26

1.25.4

1.25.2

1.25.1

1.25.0

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1.23.7

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1.23.1

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1.22.0

1.21.19

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1.9.1b3 pre-release

1.9.1b2 pre-release

1.9

1.0

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Spada Ostia

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Spada Mac Os Update